12 DIFFERENT HYALURONIC ACID MOLECULES: The Secret to Perfect Hydration and Radiant Skin

DEEP HYDRATION. INSTANT RADIANCE

How many times have you stood in front of the mirror in the morning, applying your serum and moisturizer, wishing your skincare could deliver both deep nourishment and an instant healthy glow?

At the NiKEL laboratory, we created products that do exactly that. They work continuously, gradually penetrate the skin, and provide an immediate radiant effect from the very first application.

Meet the powerful new skincare duo: NiKEL Hyaluron 12HA Serum and NiKEL Hyaluron 12HA Cream.

A SUPER HYDRATOR

These products truly deserve the title of super hydrators. Their effect can be summed up in one simple word: WOW!

Immediately after application, skin hydration is visibly improved. The complexion looks smoother, firmer, fresher, and naturally radiant—as though it is glowing from within.

What gives the NiKEL Hyaluron 12HA Serum and Cream their remarkable performance? What creates that instant radiant effect, and how does the skin remain beautifully hydrated throughout the day?

WHAT IS 12HA HYALURONIC ACID?

The effectiveness of these innovative NiKEL products is based on a unique complex of 12 different molecular weights of hyaluronic acid (12HA).

For more than 20 years, NiKEL has been developing purified pharmaceutical-grade cosmetics that combine science and nature while excluding harsh and unnecessary ingredients.

Because each hyaluronic acid molecule has a different molecular weight, the 12HA complex penetrates different layers of the skin, delivering hydration exactly where it is needed.

High Molecular Weight Molecules for surface hydration and protection

• The largest hyaluronic acid molecules provide immediate hydration to the skin's surface, strengthen the skin barrier, and help reduce moisture loss from the deeper layers.

Medium and Low Molecular Weight Molecules for firmness and deep nourishment

• Medium and low molecular weight hyaluronic acid penetrates deeper into the skin, supporting optimal cellular hydration, improving firmness, and leaving skin looking fresh, healthy, and radiant for longer.

Ultra-Low Molecular Weight Molecules replenishing moisture reserves

• Ultra-low molecular weight molecules help restore moisture reserves in the deepest layers of the skin while enhancing the penetration of other anti-ageing active ingredients.

INSTANT RESULTS. LONG-LASTING PERFORMANCE

The powerful effects of the 12HA molecular complex become visible within 15–30 minutes after applying NiKEL Hyaluron 12HA Serum and Cream.

Their intensive hydrating performance reaches up to 100% effectiveness, delivering both immediate and long-lasting hydration.

SCIENTIFICALLY DEMONSTRATED: PENETRATION FOR UP TO 24 HOURS

Research published in 2023 by Dr. Silvana Giardina, who earned her PhD in Biomedical Sciences and Human Biology at the University of Pavia, investigated the ability of 12 different molecular weights of hyaluronic acid to penetrate the skin.

The study showed that low molecular weight molecules begin penetrating the skin within 15–30 minutes, while the penetration process continues for up to 24 hours.

The research also demonstrated that lower molecular weight hyaluronic acid fully penetrates both the epidermis and dermis with 100% effectiveness, while higher molecular weight molecules achieve exceptionally high absorption of up to 69%, where they provide surface hydration and reinforce the skin barrier.

WHAT IS HYALURONIC ACID?

Hyaluronic acid is a naturally occurring substance found throughout the human body. As we age, our natural levels gradually decline.

It plays an essential role in maintaining healthy skin by retaining moisture, supporting wound healing, lubricating joints, protecting the eyes, and helping regulate inflammatory processes.

WHY IS HYALURONIC ACID SO IMPORTANT AFTER 40?

By our late forties, the body contains approximately half as much hyaluronic acid as it did in our twenties.

As natural levels decline, skin gradually loses volume, moisture, firmness, radiance, and elasticity, while fine lines and wrinkles become more visible.

In the short term, hyaluronic acid visibly plumps the skin, improves hydration, and enhances radiance.

With regular use, it strengthens the skin's natural barrier, reduces transepidermal water loss (TEWL), improves elasticity, and helps minimize the appearance of wrinkles.

CAN HYALURONIC ACID HARM THE SKIN?

Because hyaluronic acid is naturally present in the body, it is exceptionally skin-friendly.

Its outstanding safety profile and proven hydrating benefits make it one of the essential ingredients in an effective skincare routine.

WHAT MAKES NiKEL HYALURON 12HA DIFFERENT?

NiKEL already offers premium hyaluronic acid skincare enriched with vitamins. The new NiKEL Hyaluron 12HA line introduces a different innovation.

NiKEL HYALURON + VITAMINS

The existing range combines hyaluronic acid with vitamins C, E, and B.

Its advanced liposomal Vitamin C technology encapsulates pure Vitamin C within ceramide microcapsules, maximizing skin penetration while minimizing irritation.

THE NEW HYALURON 12HA LINE FEATURES 12 CAREFULLY SELECTED MOLECULAR WEIGHTS OF HYALURONIC ACID

Each molecule performs a different function according to its size:

High molecular weight molecules instantly hydrate and firm the skin's surface.
Medium molecular weight molecules replenish moisture deeper within the skin for long-lasting hydration.
Low and ultra-low molecular weight molecules reach the deepest layers, restoring moisture reserves, supporting collagen and elastin, improving skin volume, and visibly reducing the appearance of wrinkles.

The concentration of hyaluronic acid in NiKEL formulations is optimized for maximum performance, while Hyaluron 12HA Serum and Cream deliver results that are both immediate and long-lasting.

WHAT DOES WELL-HYDRATED SKIN LOOK LIKE?

Healthy, beautiful skin begins with hydration.

Regardless of your skincare routine, maintaining continuous, deep hydration is essential for preserving youthful-looking skin.

While skin ageing is a natural biological process influenced by genetics, it is also accelerated by external factors such as UV radiation, pollution, poor nutrition, lifestyle, stress, and environmental damage.

Consistent hydration helps slow many visible signs of ageing.

7 SIGNS OF WELL-HYDRATED SKIN

Deep hydration helps support healthier, younger-looking skin. Well-hydrated skin typically shows:

1. Improved elasticity
2. Smoother texture
3. Better volume and fullness
4. Reduced dehydration lines
5. A stronger skin barrier
6. Healthier overall skin condition
7. A naturally radiant, fresh complexion

NiKEL Hyaluron 12HA Serum and Cream are suitable for all skin types, especially dehydrated, dull, and tired-looking skin.

They contain no harsh or harmful ingredients, are dermatologically tested, and, naturally, are not tested on animals.

Experience the NiKEL Hyaluron 12HA collection.

NiKEL Natural Cosmetics.